Yes! The bad news is that PCOS can have a negative impact upon fertility, often by impacting or preventing ovulation, and by increasing the risks for general health issues like weight, insulin resistance, blood pressure etc. The good news is that the fertility issues are very treatable with high success rates. Most women with PCOS may only need oral medications like Letrozole to conceive. A healthy lifestyle significantly improves the chances for success with or without fertility treatment.