There are steps you can take during your period to prevent TSS. Tampons should be changed every 4 to 8 hours. Using the lowest absorbency tampon will also minimize your risk. Alternating tampons and sanitary napkins, when possible, especially is your blood flow is very light is also helpful in The larger and more absorbent tampons put you at higher risk are for TSS. Even if you have a light day and less blood flow, you still need to change your tampon every 4 to 8 hours.